Taking a medication? Start here.
Absolute Risk & NNT
What the trial actually showed — not the relative-risk headline. Translate the numbers into how many people had to be treated to help one.
Run Medication Reality Check →Nutrient Depletion Flags
Statins, metformin, PPIs, diuretics and more deplete specific nutrients. See what your prescription may affect — and why it matters before you stack.
Check Drug-Nutrient Depletion →Physician + Rabbi Discussion Sheet
One-page printable summary: trial evidence, nutrient depletions, dose/form used, kosher status, capsule shell, and questions for your prescribing clinician and your rav.
Generate the sheet →Interactive tools — built on the same four rules
Kosher Stack Builder
Pick your goal and constraints (pareve only, Chalav Yisrael, fish-gelatin ok, capsule shell). Get a tier-ranked stack with kosher certification status.
Build my stackMedication & Nutrient Depletion Check
Pick your medications. See which nutrients they may deplete — and which kosher-certified replacements have human evidence.
Run checkBiomarker Testing Roadmap
Starter panel for your physician plus the 8-test at-home library (OmegaQuant, TruDiagnostic, Everlywell, ZRT, Ulta) — kashrut-flagged.
Build roadmapCardiovascular Longevity Score
Score your heart health across 8 evidence-based factors (diet, activity, sleep, BMI, BP, cholesterol, glucose, nicotine).
Take the scorePhysician & Rabbi Discussion Sheet
One-page printable summary covering trial evidence, nutrient interactions, kosher status, and halacha-aware questions.
Generate sheetKosher Supplement Verifier
Look up a supplement ingredient or product brand. Get a three-state verdict — Certified ✓, Self-claimed (verify with rav), or No claim — plus the label-check list.
Verify a supplement ↓Kosher Stack Builder
Medication & Nutrient Depletion Check
Or browse all 40 medications by category →
Smoking accelerates turnover of antioxidant nutrients and introduces cadmium, which displaces zinc and lowers selenium bioavailability. The most consistent depletions are vitamin C (plasma levels run ~4× lower than non-smokers), vitamin E, folate, B6, and B12. The combined B-vitamin shortfall raises homocysteine, compounding cardiovascular risk already elevated by smoking itself.
Two large randomized trials — ATBC (29,133 smokers, β-carotene 20 mg/day) and CARET (18,314 smokers and asbestos-exposed workers, β-carotene 30 mg/day with retinyl palmitate) — both showed an 18–28% increase in lung cancer and higher all-cause mortality in the supplemented groups. CARET's follow-up found the elevated risk persisted after stopping. Get carotenoids from food instead (orange and dark leafy vegetables, where carotenoids come bundled with the cofactors that keep them protective).
Reasonable repletion targets if you smoke or recently quit
For carotenoids and vitamin E, choose food sources — nuts, seeds, leafy greens, colored vegetables — rather than isolated high-dose supplements.
Smoking is widely discouraged by contemporary poskim on pikuach nefesh grounds (e.g., R’ Moshe Feinstein, R’ Eliezer Waldenberg, R’ Ovadia Yosef). This section is offered for those currently smoking or in the recovery window — nutrient support is not an endorsement of continued use. Discuss your situation with your rav and physician.
Citations: ATBC Study (NEJM 1994) · CARET Trial (NEJM 1996) · Albanes 1996 JNCI · CARET 6-yr follow-up. Educational content only — not medical advice. Discuss specifics with your physician and your rav.
Don't see your medication? Submit it for physician review →
We add new entries weekly. Submissions are reviewed by Dr. Sandlow before being added to the public library so every entry has cited evidence and verified kosher routing.
At-Home Test Library
Or browse all 8 at-home tests by sample type →
Don't see your test? Submit it for review →
We add new tests as new evidence and partner options emerge. Submissions reviewed by Dr. Sandlow before public publication.