Cognitive Health
Kosher supplements for cognitive longevity
Brain aging is multi-factorial. These are the evidence-graded options with kosher-verified SKUs — from the strong RCT data for creatine in older adults to the modest but consistent data for lion's mane in early cognitive impairment.
Evidence tiers apply across this page. Tier 1 = human RCTs with meaningful endpoints. Tier 2 = human RCT data, not longevity primary endpoints. Tier 3 = limited or mechanistic human data. Community = no evidence tier; kashrut notes only. See full ranked list →
Creatine Monohydrate
Tier 1
3–5 g/day
500+ RCTs. Consistently improves cognitive performance under stress and in older adults. Pareve synthetic. OU/Badatz available.
GlyNAC (Glycine + NAC)
Tier 1
~100 mg/kg each
Kumar 2023: improved cognitive function, mitochondrial health, oxidative stress in older adults. Pareve amino acids.
Ashwagandha (KSM-66)
Tier 2
300–600 mg/day
Reduces cortisol and stress response. Chronic cortisol elevation is a major cognitive aging driver. Plant-derived pareve.
Lion's Mane
Tier 3
500–1000 mg/day
Mori 2009 RCT: significant cognitive improvement in mild impairment, reversed on stopping. Mushroom = pareve (ask your rav on supervision).
Phosphatidylserine
Tier 3
100–300 mg/day
FDA qualified health claim for cognitive decline. ⚠ Must be soy-derived (pareve) — historical bovine source is non-kosher.
Vitamin B12
Community
Varies by form
Critical for cognitive aging. Deficiency causes reversible neurological damage. Metformin users especially at risk. Widely OU certified.
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