Pulsetto
Direct neck-clip tVNS device with measured pulse parameters. Stronger published spec transparency than wearable-only competitors.
Shop Pulsetto ↗Grade B — Anxiety and HRV signals are real; longevity endpoint data is preliminary.
Transcutaneous vagus nerve stimulation (tVNS) has RCT data for anxiety reduction, HRV improvement, and inflammatory marker decrease. The implantable VNS form is FDA-cleared for treatment-resistant depression and refractory epilepsy; the consumer transcutaneous form is a lower-dose proxy with shorter trial durations.
Direct neck-clip tVNS device with measured pulse parameters. Stronger published spec transparency than wearable-only competitors.
Shop Pulsetto ↗
Wearable mechanoreceptor stimulation (vibration patterns), not direct vagal current. Calming-protocol RCT data, but a different mechanism than true tVNS — included here for category breadth.
Shop Apollo ↗No. Pulsetto delivers transcutaneous electric current to the vagus nerve at the neck. Apollo Neuro is a wrist vibration device — separate mechanism and separate RCT base. Both have a place; they are not interchangeable.
No. Implantable VNS is a different category, FDA-cleared for specific psychiatric and neurological indications. This page is the consumer non-implantable category.
Direct PubMed links to the strongest published human studies behind this category. We update these as new trials emerge. Citations are educational — not endorsements of any specific brand or treatment.